Coexpression of Linked Genes in Mammalian Genomes Is Generally Disadvantageous
نویسندگان
چکیده
منابع مشابه
Coexpression of linked genes in Mammalian genomes is generally disadvantageous.
Similarity in gene expression pattern between closely linked genes is known in several eukaryotes. Two models have been proposed to explain the presence of such coexpression patterns. The adaptive model assumes that coexpression is advantageous and is established by relocation of initially unlinked but coexpressed genes, whereas the neutral model asserts that coexpression is a type of leaky exp...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2008
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msn101